Free PTCB Federal Requirements Practice Test 2026 — CPhT Exam Questions

This free PTCB Federal Requirements practice test covers federal pharmacy law including DEA controlled substance schedules, recordkeeping (DEA 222), FDA recalls, HIPAA, OSHA, USP <800>, and REMS programs. Each question includes a detailed explanation — perfect for PTCB / CPhT exam prep.

Key Topics in PTCB Federal Requirements

6 Free PTCB Federal Requirements Practice Questions with Answers

Sample Question 1 — Pharmacy Law and Regulations

Which agency is responsible for enforcing the Controlled Substances Act in the United States?

  1. A. Food and Drug Administration (FDA)
  2. B. Drug Enforcement Administration (DEA) (Correct answer)
  3. C. Centers for Disease Control and Prevention (CDC)
  4. D. U.S. Department of Agriculture (USDA)

Correct answer: B

Explanation: The Drug Enforcement Administration (DEA) is responsible for enforcing the Controlled Substances Act and regulating the handling of controlled substances.

Sample Question 2 — Pharmacy Law and Regulations

What is the maximum number of refills allowed for a Schedule III controlled substance prescription?

  1. A. Three
  2. B. Five (Correct answer)
  3. C. Six
  4. D. Unlimited

Correct answer: B

Explanation: Schedule III controlled substances may be refilled up to five times within six months from the date of issue, according to federal regulations.

Sample Question 3 — Pharmacy Law and Regulations

Which of the following statements is true regarding prescription requirements for controlled substances?

  1. A. Prescriptions for Schedule II drugs can be refilled.
  2. B. Schedule IV prescriptions do not require a prescriber's signature.
  3. C. All controlled substance prescriptions require a DEA number. (Correct answer)
  4. D. Electronic prescriptions for Schedule II drugs are never allowed.

Correct answer: C

Explanation: All controlled substance prescriptions must include the prescriber’s DEA number to ensure legality and traceability.

Sample Question 4 — Pharmacy Law and Regulations

According to the Health Insurance Portability and Accountability Act (HIPAA), which of the following is considered Protected Health Information (PHI)?

  1. A. A patient's medical record number (Correct answer)
  2. B. The cost of a medication
  3. C. A pharmacy's business phone number
  4. D. General health statistics

Correct answer: A

Explanation: Protected Health Information (PHI) includes any information that can identify a patient, such as their medical record number, under HIPAA regulations.

Sample Question 5 — Pharmacy Law and Regulations

Under federal law, what must be included on the label of a dispensed prescription medication?

  1. A. Patient's social security number
  2. B. Prescriber's license number
  3. C. Pharmacy's contact information (Correct answer)
  4. D. Patient's insurance policy number

Correct answer: C

Explanation: The label of a dispensed prescription must include the pharmacy’s contact information to ensure patients can reach out for inquiries or issues.

Sample Question 6 — Pharmacy Law and Regulations

Which form is used to order Schedule II controlled substances in the United States?

  1. A. DEA Form 222 (Correct answer)
  2. B. DEA Form 41
  3. C. DEA Form 106
  4. D. DEA Form 224

Correct answer: A

Explanation: DEA Form 222 is required for the ordering and transferring of Schedule II controlled substances as per federal regulations.

About the PTCB / PTCE Exam

Other PTCB Practice Topics

Start the free PTCB Federal Requirements practice test now | 10-question quick start | All PTCB topics